Key result
Medication non-adherence affects ~60% of Middle Eastern heart failure patients, driven largely by socioeconomic factors.
Why the study?
Medication adherence among heart failure patients in the Middle East is a critical, under-explored issue with significant socio-economic and clinical influencing factors.
Systematic Review (n=3,158)
Effect estimate: 60% average non-adherence rate
There is a high rate of medication non-adherence (60%) among heart failure patients in the Middle East, highlighting a critical need for targeted interventions addressing socioeconomic and educational barriers.
Requires targeted adherence interventions for Middle Eastern HF patients; extends evidence on socioeconomic barriers to this region.
Medication adherence among heart failure (HF) patients in the Middle East remains a critical, under-explored issue. This systematic review examines medication adherence rates and their influencing factors in this region. A search of PubMed, Scopus, and Google Scholar identified 12 studies published between 2013 and 2023, revealing an average non-adherence rate of 60%. Influential factors include socioeconomic status, education, psychiatric conditions, and medication-related issues. Significant gaps in research methodologies and reporting were noted. The review highlights the impact of socio-economic determinants on adherence and calls for more robust research and targeted interventions to address these barriers. Improving patient education and healthcare provider communication are crucial to enhancing adherence rates. These findings underscore the importance of addressing regional challenges through tailored approaches and suggest further studies are needed to develop effective strategies for improving adherence among HF patients in the Middle East.
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Alfaqeeh et al. (2025) conducted a systematic review in Heart failure (n=3,158). Medication non-adherence factors was evaluated on Medication non-adherence rate (60% average non-adherence rate). Medication non-adherence among heart failure patients in the Middle East averages 60%, significantly influenced by socioeconomic status, education, psychiatric conditions, and medication-related issues.
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