December 1, 2006The International Journal of Psychiatry in Medicine
A Cohort Study to Assess the Impact of Depression on Patients with Kidney Disease
Key result
Depression was not associated with mortality in patients with kidney disease after adjusting for confounders, but a higher number of depressive symptoms strongly predicted lower quality of life.
Why the study?
Does depression impact mortality and quality of life in patients with kidney disease?
Population
125 patients with kidney disease undergoing renal replacement therapy, seen from 1996 to 2004 at Hospital…
Design
Cohort
Follow-up
mean 77.6 months
Authors
Discussion
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Implication
Findings support addressing depressive symptoms to enhance QoL in kidney disease; leaves open mortality effects after adjustment.
Study Design
Type
Cohort (n=125)
Multicenter
No
Structured PICO
Does depression impact mortality and quality of life in patients with kidney disease?
P
Population
125 patients with kidney disease undergoing renal replacement therapy, followed for a mean of 77.6 months.
E
Exposure
Depression (assessed by Beck Depression Inventory)
O
Outcome
Mortality and quality of life (assessed by SF-36)
In patients with kidney disease on renal replacement therapy, depression significantly impairs quality of life but is not an independent predictor of mortality.
Cite This Study
Zimmermann et al. (2006) conducted a cohort in Kidney disease (n=125). Depression was evaluated on Mortality and quality of life. Depression was not associated with mortality in patients with kidney disease after adjusting for confounders, but a higher number of depressive symptoms strongly predicted lower quality of life.