What question did this study set out to answer?

To compare the physicochemical characteristics, stability, antioxidant capacity, DNA cleavage, and antibacterial activities of silver nanoparticles synthesized via plant extract versus chemical reduction.

November 12, 2018Artificial Cells Nanomedicine and BiotechnologyOpen Access

A comparative study of stability, antioxidant, DNA cleavage and antibacterial activities of green and chemically synthesized silver nanoparticles

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Authors

MMMohammad Mousavi-KhattatIsfahan University of Technology MKMehrnaz KeyhanfarFlinders University ARAmir RazmjouEdith Cowan University

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Implication

Comparative in vitro study demonstrates superior antibacterial and antioxidant efficacy in green-synthesized silver nanoparticles, highlighting plant-based biomanufacturing advantages.

Key Points

To compare the physicochemical characteristics, stability, antioxidant capacity, DNA cleavage, and antibacterial activities of silver nanoparticles synthesized via plant extract versus chemical reduction.
Synthesized silver nanoparticles using Datura stramonium leaf extract as a biogenic reducing agent and sodium citrate as a chemical reducing agent.
Characterized particle size and morphology using UV-Visible spectroscopy, dynamic light scattering (DLS), atomic force microscopy (AFM), and transmission electron microscopy (TEM).
Assessed bioactivity through antioxidant assays, plasmid DNA cleavage analysis, and antibacterial growth inhibition via minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) assays.
Green-synthesized nanoparticles displayed a spherical morphology with a narrow size distribution, whereas chemically synthesized nanoparticles had a smaller mean size but a broader size range.
Green-synthesized nanoparticles exhibited potent antioxidant capacity, marked DNA cleavage activity, and high antibacterial efficacy; conversely, chemically synthesized nanoparticles showed no antioxidant activity and lower antibacterial and DNA cleavage activities.

Cite This Study

Mousavi-Khattat et al. (2018) studied this question.

synapsesocial.com/papers/6ab4ae42f0af80d90cfd7835 https://doi.org/10.1080/21691401.2018.1527346

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Implication

Comparative in vitro study demonstrates superior antibacterial and antioxidant efficacy in green-synthesized silver nanoparticles, highlighting plant-based biomanufacturing advantages.

A comparative study of stability, antioxidant, DNA cleavage and antibacterial activities of green and chemically synthesized silver nanoparticles

Discussion

Member takes

Implication

Key Points

Cite This Study

A comparative study of stability, antioxidant, DNA cleavage and antibacterial activities of green and chemically synthesized silver nanoparticles

Discussion

Member takes

Implication

Key Points

Cite This Study

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