Key result
Severe gastric ulcer bleeding is linked to transient ECG changes in ~69% of patients.
Why the study?
Changes in the electrocardiogram following sudden blood loss have been observed but were not well distinguished from those in chronic anemias.
Does acute loss of blood cause transient electrocardiographic changes?
Observational (n=16)
Does acute loss of blood cause transient electrocardiographic changes?
Acute blood loss can cause transient electrocardiographic abnormalities that resolve within days, independent of persistent anemia.
Answers are grounded in this paper and cite their sources.
ECG changes may follow acute blood loss; leaves open their prognostic value and management implications today.
Article1 March 1944ELECTROCARDIOGRAPHIC CHANGES AFTER ACUTE LOSS OF BLOODDAVID SCHERF, M.D., S. D. KLOTZ, M.D.DAVID SCHERF, M.D., S. D. KLOTZ, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-20-3-438 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptChanges in the electrocardiogram following sudden blood loss have been observed with increasing frequency. The pioneer observations were casual and isolated, and the alterations were not distinguished from those noted in chronic anemias.1, 3, 7, 11, 19 The abnormal electrocardiogram was usually ascribed to the anemia.Recently Scherf, Reinstein and Klotz17reported abnormal electrocardiograms after profuse hemorrhage in gastric ulcer. The tracing was altered in 11 of 16 such cases, and the changes were pronounced in eight of them. The electrocardiogram became normal again within a few days. The hemoglobin level often had remained low or had fallen farther when...Bibliography1. ASCHENBRENNER R: Magenblutung und Anoxie des Herzmuskels, Ztschr. f. klin. Med., 1934, cxxvii, 160. Google Scholar2. BAZETT HC: Blood volume and cardiovascular adjustments, Am. Heart Jr., 1941, xxi, 423. CrossrefGoogle Scholar3. BLOCH C: Herzbeschwerden und Elektrokardiogrammbefunde bei Anämie, Acta med. Scandinav., 1938, xciii, 543. Google Scholar4. BOYDSCHERF LJD: The electrocardiogram after mechanical injury of the inner surface of the heart, Bull. New York Med. Col., Flower & Fifth Ave. Hosps., 1940, iii, 1. Google Scholar5. BÜCHNERVON LUCADOU FW: Elektrokardiographische Veranderungen und disseminierte Nekrosen des Herzmuskels bei experimenteller Coronarinsuffizienz, Beitr. z. path. Anat. u. z. allg. Path., 1934, xciii, 169. Google Scholar6. DENNISMOORE JRM: Potassium changes in the functioning heart under conditions of ischemia and of congestion, Am. Jr. Physiol., 1938, cxxiii, 443. 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To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication September 17, 1942.From the Department of Medicine of the New York Medical College, Flower and Fifth Avenue Hospitals (Metropolitan Hospital Service). PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byElektrokardiographische Veränderungen nach akutem Blutverlust bei KaninchenSchock und KollapsMASSIVE HEMORRHAGE FROM PEPTIC ULCER: A CAUSE OF MYOCARDIAL INFARCTION IN THE AGED†Anginöse Schmerzen und ihre DifferentialdiagnoseAn evaluation of the term "coronary insufficiency"Variations of form of T waves in auricular flutter and auricular fibrillation, associated with changes of rateAnginöse Schmerzen und ihre DifferentialdiagnoseOther QRS-T Patterns that May Be Mistaken for Myocardial InfarctionAcute Coronary Insufficiency Due to Acute Hemorrhage: An Analysis of One Hundred and Three CasesThe effect of ergotamine tartrate on the abnormal electrocardiogram in patients previously prepared with tetraethylammonium chlorideELECTROCARDIOGRAPHIC STUDY OF TYPHOID MYOCARDITISThe Use of Electrocardiograms in Medicine 1 March 1944Volume 20, Issue 3Page: 438-452KeywordsAnemiaBloodElectrocardiographyGastric ulcersHemoglobinHemorrhageHospital medicine ePublished: 1 December 2008 Issue Published: 1 March 1944 PDF downloadLoading ...
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Scherf et al. (1944) conducted an observational in Acute blood loss / gastric ulcer hemorrhage (n=16). Profuse hemorrhage was evaluated on Abnormal electrocardiogram. Profuse hemorrhage from gastric ulcer resulted in altered electrocardiographic tracings in 68.8% (11 of 16) of cases, which normalized within a few days.
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