Key result
ACE inhibitors remain essential for cardiorenal disease, but managing adverse effects is key to compliance.
Why the study?
ACE inhibitors are widely used for multiple cardiovascular and renal conditions, but awareness of their side-effects is crucial to improve patient compliance.
A narrative review highlighting the classes, clinical indications, and the importance of recognizing side effects of ACE inhibitors in general medicine.
Angiotensin-converting enzyme (ACE) inhibitors are a class of drugs commonly used in the management of hypertension, congestive heart failure, cerebrovascular disease, stable coronary heart disease and diabetes-associated nephropathy. ACE inhibitors are divided into three classes, namely sulphydryl-containing ACE inhibitors structurally related to captopril, carboxyl-containing ACE inhibitors structurally related to enalapril, and phosphorus-containing ACE inhibitors structurally related to fosinopril. Though these classes of drugs are important in the treatment of the above conditions, they are not without side-effects. It is very important for clinicians to be aware of these side-effects so that patients can be warned, and compliance can be improved.
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MLI Mashitisho (2012) conducted a review in Hypertension, congestive heart failure, cerebrovascular disease, stable coronary heart disease and diabetes-associated nephropathy. Angiotensin-converting enzyme (ACE) inhibitors was evaluated. Angiotensin-converting enzyme (ACE) inhibitors are important in managing various cardiovascular and renal conditions, but clinicians must be aware of their side-effects to improve patient compliance.
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