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Reports clearance of disseminated adenovirus following extracorporeal life support and antiviral therapy in a critically ill neonate, highlighting salvage treatment options.
A 5-day-old neonate was admitted with chest radiograph showing right-lung opacification. This, together with a severe adenovirus (AdV) viremia (11.8 million copies/mL), indicated severe adenovirus pneumonitis. She was given extracorporeal membrane oxygenation (ECMO), steroids and intravenous cidofovir. After clearing her AdV and 33 days of ECMO, she continued to require nocturnal ventilator support, after transfer back to her local hospital.
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Jayaweera et al. (2024) studied this question.
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