Key result
Postoperative RT and chemotherapy in breast cancer survivors are linked to cardiotoxicity and pneumonitis.
Why the study?
Concerns exist about the risk of acute and chronic side effects in breast cancer survivors treated with postoperative radiation therapy and chemotherapy due to their long expected survival.
Adjuvant treatments for breast cancer, including radiation and chemotherapy, are associated with a wide range of acute and chronic complications such as cardiac toxicity.
Alerts clinicians to monitor long-term toxicities in breast cancer survivors; leaves open precise risk quantification in prospective cohorts.
Postoperative radiation therapy (RT) and chemotherapy,both reduces the risk of local recurrence and extends overall survival in patients with breast cancer (BC). Concerns have, however, been raised about the risk of acute and chronic side effects in breast cancer survivors as the number of treated individuals is large and their expected survival is long compared to most patients with other malignant diseases. Cardiac toxicity, reproductive dysfunction, pneumonitis (RP),arm lymph edema, neuropathy, skin changes are examples of the wide range of complications that has been associated with adjuvant treatment.
No takes yet. Share an insight, caveat, or question.
Sushma Agrawal (2014) conducted a review in Breast cancer. Postoperative radiation therapy and chemotherapy was evaluated. Postoperative radiation therapy and chemotherapy in breast cancer survivors are associated with complications such as cardiac toxicity, reproductive dysfunction, and pneumonitis.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: