Repeated Fetal Losses and the Lupus Anticoagulant

Letters and Corrections15 December 1988Repeated Fetal Losses and the Lupus AnticoagulantAnne Francois, MD, Marc Freund, MD, Fernand Daffos, MD, Philippe Remy, MD, Martine Aiach, MD, Christian Jacquot, MDAnne Francois, MDSearch for more papers by this author, Marc Freund, MDSearch for more papers by this author, Fernand Daffos, MDSearch for more papers by this author, Philippe Remy, MDSearch for more papers by this author, Martine Aiach, MDSearch for more papers by this author, Christian Jacquot, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-109-12-993 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editor: Combined therapy with prednisone and low doses of aspirin has been reported to reduce the risk for fetal loss in women with the lupus anticoagulant (1, 2). We report a case in which a woman with the lupus anticoagulant had had three successive fetal losses while receiving this combined therapy. The outcome of a fourth pregnancy was favorable when she was given high-dose intravenous polyvalent immunoglobulin therapy.A 24-year-old woman had episodes of deep venous thrombosis and pulmonary embolism when she was 18, 19, and 22 years of age. She was found to have the lupus anticoagulant...References1. BranchScottKochenourHershgold DJNE. Obstetric complications associated with the lupus anticoagulant. N Engl J Med. 1985;313:1322-6. CrossrefMedlineGoogle Scholar2. LubbeButlerPalmerLiggins WWSC. Fetal survival after prednisone suppression of maternal lupus anticoagulant. Lancet. 1983;1:1361-3. CrossrefMedlineGoogle Scholar3. LeveryKoontzLiuHowell JWYR. Immunological thrombocytopenia in pregnancy: use of antenatal immunoglobulin therapy; case report and review. Obstet Gynecol. 1985;66:415-35. Google Scholar4. ImbachBaradunD'Apuzzo PSV. High dose intravenous gamma-globulin for idiopathic thrombocytopenic purpura in childhood. Lancet. 1981;1:1228-31. CrossrefMedlineGoogle Scholar5. LeicklyBuckley FR. Successful treatment of autoimmune hemolytic anemia in common variable immunodeficiency with high-dose intravenous gamma globulin. Am J Med. 1987;82:159-62. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Anne Francois, MD; Marc Freund, MD; Fernand Daffos, MD; Philippe Remy, MD; Martine Aiach, MD; Christian Jacquot, MDAffiliations: Hôpital Broussais 75014 Paris, France PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byImmune modulation of i.v. immunoglobulin in women with reproductive failurePrevention of recurrent miscarriage for women with antiphospholipid antibody or lupus anticoagulantAntiphospholipid Antibodies: Effects on Trophoblast and Endothelial CellsRecurrent Pregnancy LossAutoimmune disease as a cause of reproductive failureAn update on the role of immunotherapy in reproductive failureNephrological and obstetric complications of the antiphospholipid syndromeRecurrent Pregnancy Loss With Antiphospholipid AntibodyTherapy for miscarriage associated with antiphospholipid antibody or lupus anticoagulantClinical Uses of Intravenous Immunoglobulin in PregnancyPregnancy Complicated by the Antiphospholipid SyndromeIntérêt des immunoglobulines intraveineuses au cours du syndrome des antiphospholipidesThe Role of Placental Trophoblast in the Pathophysiology of the Antiphospholipid Antibody SyndromeClinical uses of intravenous immunoglobulin in pregnancyAntiphospholipid Antibodies and Recurrent Pregnancy LossIntravenous Immunoglobulin for Treatment of Recurrent Pregnancy LossAlternative Treatment to Lymphocyte Immunization for Treatment of Recurrent Spontaneous Abortion: Immunotherapy With Intravenous Immunoglobulin for Treatment of Recurrent Pregnancy Loss: American ExperienceUltrasonographic findings of pregnancy losses after treatment for recurrent pregnancy loss: intravenous immunoglobulin versus placeboFaktor XII- (Hageman) Mangel bei Frauen mit habituellen Aborten. 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Brewer, RNThe role of IVIG in the management of patients with antiphospholipid antibodies and recurrent pregnancy lossesThe Role of IVIG in the Management of Patients with Antiphospholipid Antibodies and Recurrent Pregnancy LossesSystemischer Lupus Erythematodes und Schwangerschaft: Eine ÜbersichtLupus Anticoagulants, Anticardiolipin Antibodies, and Fetal Loss: A Case–Control StudyThe use of IVIG for the treatment of recurrent spontaneous abortionAutoantibodies, alloantibodies and reproductive successAntiphospholipid Antibodies and ReproductionPregnancy-associated immunological disordersAntiphospholipid Antibodies and Recurrent Pregnancy LossIntravenous Gamma-Globulin, Antiphospholipid Antibodies, and PregnancyAnn Parke, MBBS, Donald Maier, MD, Daniel Wilson, BA, John Andreoli, MD, Mark Ballow, MD 15 December 1988Volume 109, Issue 12Page: 993-994KeywordsAnticoagulant therapyAnticoagulantsAspirinDeep vein thrombosisPregnancyPulmonary embolismRisk management ePublished: 1 December 2008 Issue Published: 15 December 1988 PDF downloadLoading ...