Key result
Small apical muscular VSDs close spontaneously in ~57% of children, rising to ~90% when diagnosed neonatally.
Why the study?
The frequency and timing of spontaneous closure of small apical muscular ventricular septal defects, especially when diagnosed in the neonatal period, were not well established.
Population
42 cases with apical muscular ventricular septal defects aged 1 day to 13 years
Comparison
Spontaneous closure vs no closure of ventricular septal defects
Design
Retrospective observational study
Follow-up
At least two years
Authors
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May support initial expectant management in apical muscular VSDs; leaves open predictors of closure and need for prospective trials.
Observational (n=42)
No
Small apical muscular ventricular septal defects diagnosed in the neonatal period have a high rate of spontaneous closure (90%), supporting conservative follow-up especially in the first two years of life.
Atalay et al. (2005) conducted an observational in Small apical muscular ventricular septal defects (n=42). Small apical muscular ventricular septal defects was evaluated on Spontaneous closure of the ventricular septal defect. Spontaneous closure occurred in 57.1% of children with small apical muscular ventricular septal defects, including 90% of cases diagnosed in the neonatal period.
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