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September 16, 2022Disease MarkersOpen Access

Does Hyponatremia Affect the Short-Term Outcomes of Colorectal Cancer Surgery: A Propensity Score Matching Analysis

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Key result

Preoperative hyponatremia was an independent predictor of overall complications after colorectal cancer surgery (OR 1.856; 95% CI 1.148-3.001; P=0.012).

Why the study?

Does preoperative hyponatremia increase the risk of short-term complications in patients undergoing colorectal cancer surgery?

Population

6,730 patients who underwent primary colorectal cancer surgery at a single clinical center between January…

Comparison

Preoperative hyponatremia (n=184) vs Normal preoperative sodium levels

Design

Cohort

Follow-up

short-term (postoperative)

Authors

XLXiao-Yu LiuKunming Medical UniversityBZBin ZhangThe Affiliated Yongchuan Hospital of Chongqing Medical UniversityBKBing KangShandong Provincial Hospital

Discussion

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Member takes

Overview

Preoperative hyponatremia was associated with higher complication rates after CRC surgery; leaves open whether correction improves outcomes in prospective trials.

Study Design

Type

Observational (n=6,730)

Multicenter

No

Structured PICO

Does preoperative hyponatremia increase the risk of short-term complications in patients undergoing colorectal cancer surgery?

P
Population
6,730 patients who underwent primary colorectal cancer surgery at a single center between 2011 and 2021.
E
Exposure
Preoperative hyponatremia (n=184)
C
Comparator
Normal preoperative sodium levels (n=6546, with 184 matched via propensity score matching)
O
Outcome
Short-term outcomes (overall complications)safety

Main Result

Odds Ratio: 1.856 (95% CI 1.148–3.001)

p-value: p=0.012

Preoperative hyponatremia is associated with an increased risk of short-term complications following colorectal cancer surgery.

Cite This Study

Liu et al. (2022) conducted an observational in Colorectal cancer (CRC) surgery (n=6,730). Preoperative hyponatremia vs. Normal sodium was evaluated on Overall complications (OR 1.856, 95% CI 1.148-3.001, p=0.012). Preoperative hyponatremia was an independent predictor of overall complications after colorectal cancer surgery (OR 1.856; 95% CI 1.148-3.001; P=0.012).

synapsesocial.com/papers/6ab4bfa02dd9dd6133df6ec2https://doi.org/10.1155/2022/5109999
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