Key result
Clinical, laboratory, and intraoperative variables, including ASA III score, CRP, perforated appendicitis, and surgery time, were significantly associated with postoperative complications (p<0.05).
Why the study?
What clinical, laboratory, and intraoperative variables are associated with postoperative complications in patients over 50 years old with acute appendicitis?
Cross-Sectional (n=206)
What clinical, laboratory, and intraoperative variables are associated with postoperative complications in patients over 50 years old with acute appendicitis?
In patients over 50 with acute appendicitis, factors such as ASA III score, elevated CRP, perforated appendicitis, and longer surgery time are significant predictors of postoperative complications.
Answers are grounded in this paper and cite their sources.
Several factors associated with complications after appendicitis surgery in patients >50; leaves open need for prospective validation before clinical use.
Objective. To determine the impact of clinical, laboratory, and intraoperative variables on postoperative complications in patients over 50 years of age with acute appendicitis. Material and methods. An observational, analytical, cross-sectional study included patients over 50 years old who underwent surgery for acute appendicitis. The sample included 206 patients, and clinical, laboratory, and surgical data were collected from medical records. The Clavien—Dindo classification was used to estimate postoperative complications. Data were analyzed using SPSS software v.28. Results. Postoperative morbidity rate was 30.09%. Clinical variables such as age, male gender, duration of illness, presence of type 2 diabetes (DM2), and arterial hypertension (HTA), along with laboratory variables such as leukocyte count, Neutrophil-to-Lymphocyte Ratio (NLR), blood glucose, creatinine, and C-reactive protein (CRP), were significantly associated with postoperative complications (p<0.05). In addition, intraoperative variables such as surgery time, ASA III score, perforated appendicitis, peritonitis, laparoscopic appendectomy and hospital stay were significantly associated with postoperative complications (p<0.05). Conclusion. This study highlights the importance of various clinical, laboratory, and intraoperative variables in predicting postoperative complications in patients over 50 years old with acute appendicitis. ASA III score, CRP, perforated appendicitis, and surgery time are associated with postoperative complications.
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Franco-Alva et al. (2024) conducted a cross-sectional in Acute appendicitis (n=206). Clinical, laboratory, and intraoperative variables was evaluated on Postoperative complications (Clavien-Dindo classification) (p=<0.05). Clinical, laboratory, and intraoperative variables, including ASA III score, CRP, perforated appendicitis, and surgery time, were significantly associated with postoperative complications (p<0.05).
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