In vivo upconversion: Photoresponsive dithienylethene ligands decorated onto lanthanide-doped, upconverting nanoparticles are used to modulate the amount of emission from the nanoparticles. The hybrid system can be toggled between ‘bright’ and ‘dark’ states by using two different types of light in living nematodes (see figure).
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Boyer et al. (2012) studied this question.
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