Key result
Conversion to nocturnal home hemodialysis in patients failing peritoneal dialysis significantly reduced plasma creatinine (from 1107 to 649 micromol/L, p=0.01) and increased standardized Kt/V.
Why the study?
Does nocturnal home hemodialysis improve clinical and biochemical indices in ESRD patients failing peritoneal dialysis?
Population
8 ESRD patients failing peritoneal dialysis converted to NHD at the University Health Network and Humber…
Comparison
Nocturnal home hemodialysis, 3-6 sessions per… vs Baseline values on peritoneal dialysis before…
Design
Cohort
Follow-up
1 year
Authors
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Supports rescue transition to nocturnal home HD after PD failure; extends limited observational data but leaves open need for RCTs.
Cohort (n=8)
Yes
Does nocturnal home hemodialysis improve clinical and biochemical indices in ESRD patients failing peritoneal dialysis?
Absolute Event Rate: 649% vs 1107%
p-value: p=0.01
Nocturnal home hemodialysis is a viable salvage therapy that improves biochemical indices in ESRD patients failing peritoneal dialysis.
Wong et al. (2007) conducted a cohort in End-stage renal disease (ESRD) failing peritoneal dialysis (n=8). Nocturnal home hemodialysis (NHD) vs. Peritoneal dialysis (baseline) was evaluated on Plasma creatinine concentration (micromol/L) (p=0.01). Conversion to nocturnal home hemodialysis in patients failing peritoneal dialysis significantly reduced plasma creatinine (from 1107 to 649 micromol/L, p=0.01) and increased standardized Kt/V.
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