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Recent evidence published in this Journal showed the protective role of the iron homeostasis regulator hepcidin (Hamp) in iron overload-related liver diseases [1]. The study by Lunova et al. elegantly demonstrated that the knockdown of hepcidin promotes hepatic inflammation and fibrogenesis after feeding mice an iron-rich diet [1].
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Kessler et al. (2014) studied this question.
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