Key result
Irradiation without chemotherapy offered little palliation or enhanced survival for patients with osteosarcoma who were able to undergo radical surgery.
Why the study?
Does radiation therapy improve palliation or survival in patients with osteosarcoma compared to surgery alone?
Population
70 patients with osteosarcoma treated at the University of California-San Francisco between 1950 and 1974
Comparison
Preoperative irradiation followed by surgery or… vs Surgery alone (n=22)
Design
Cohort
Authors
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Radiation without chemotherapy offers minimal benefit in operable osteosarcoma; leaves open its adjunctive role with modern multimodal regimens.
Observational (n=70)
No
Does radiation therapy improve palliation or survival in patients with osteosarcoma compared to surgery alone?
Radiation therapy without chemotherapy does not appear to improve palliation or survival in osteosarcoma patients eligible for radical surgery.
Beck et al. (1976) conducted an observational in Osteosarcoma (n=70). Radiation therapy vs. Surgery alone was evaluated on Palliation or enhanced survival. Irradiation without chemotherapy offered little palliation or enhanced survival for patients with osteosarcoma who were able to undergo radical surgery.
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