What is the clinical evidence from this study?

Study design: Review. Population: Depression, anxiety, and cardiovascular disease. Intervention: Depression and anxiety.

March 18, 2021Family PracticeOpen Access

Evidence for depression and anxiety as risk factors for heart disease and stroke: implications for primary care

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Key result

Depression and anxiety are linked to incident CVD and worse outcomes in existing heart disease.

Why the study?

There is ample evidence supporting depression and anxiety as risk factors for incident and recurrent cardiovascular disease, but challenges remain in treatment and prevention in primary care.

Population

Patients with depression and anxiety at risk for or with established cardiovascular disease

Design

Review of epidemiologic studies, meta-analyses, and clinical trials

Authors

ARAnnie RyderChildren's Mercy Hospital BCBeth E. CohenPreventive Cardiology

Discussion

Member takes

Implication

Mental health screening may improve CVD outcomes in primary care; extends meta-analytic evidence for integrated management.

Structured PICO

Population

Patients with depression and anxiety, including those at risk for incident cardiovascular disease and those with established cardiovascular disease.

Exposure

Mental health interventions including antidepressants, behavioral therapies, cardiac rehabilitation, and collaborative care models.

Depression and anxiety are significant risk factors for cardiovascular disease, emphasizing the need for primary care providers to screen for and manage these conditions to potentially mitigate cardiovascular risk.

Limitations

The bidirectional nature of associations between mental health and CVD risk factors makes exploring pathogenesis challenging.
The impact of mental health treatments on cardiovascular outcomes has been mixed across modalities.
Few trials have specifically targeted anxiety, and no trials have evaluated whether treating depression and anxiety prevents the development of CVD.
Challenges remain in approaches to treating depression and anxiety in primary care
Need for longitudinal studies with diverse patient populations to definitively establish mechanisms
Lack of trials evaluating whether treatment of depression and anxiety can prevent the development of CVD

Cite This Study

Ryder et al. (2021) conducted a review in Depression, anxiety, and cardiovascular disease. Depression and anxiety was evaluated. Depression and anxiety are established risk factors for incident cardiovascular disease and are associated with worse outcomes in patients with existing heart disease.

synapsesocial.com/papers/6ab4d73e8f3bb436e381513f https://doi.org/10.1093/fampra/cmab031

View Full Paper

Ask AI

Bookmark

Evidence for depression and anxiety as risk factors for heart disease and stroke: implications for primary care

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Evidence for depression and anxiety as risk factors for heart disease and stroke: implications for primary care

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider