Key result
Low ligation of the IMA speeds bowel recovery vs. high ligation with similar 2-year survival.
Why the study?
There is controversy regarding whether high or low ligation of the inferior mesenteric artery during rectal cancer surgery provides better surgical and oncological outcomes.
Population
95 patients with clinical stage I-III rectal cancer
Comparison
High ligation of IMA vs low ligation of IMA with lymph node dissection
Design
Prospective randomized study
Follow-up
2 years
Authors
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HL vs LL in rectal cancer resection; leaves open optimal ligation level for oncologic and functional outcomes.
RCT (n=95)
Feng et al. (2021) conducted an RCT in Rectal cancer (n=95). High ligation of the inferior mesenteric artery vs. Low ligation with lymph node dissection at the root of the inferior mesenteric artery was evaluated. Low ligation of the inferior mesenteric artery during rectal cancer surgery resulted in a significantly shorter time to first flatus compared to high ligation (p < .0001), with similar 2-year survival.
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