Key result
Adding ACI-TIPI score to standard ECG fails to improve diagnostic accuracy or triage in chest pain.
Why the study?
The impact of the ACI-TIPI on triage and diagnosis of chest pain patients in rural hospitals was not established.
Does the use of the ACI-TIPI score improve diagnostic accuracy and triage in patients with chest pain in rural hospitals?
RCT (n=1,861)
Open-label
Hospitals randomly assigned to begin with ACI-TIPI on or off, then alternated monthly
Yes
Does the use of the ACI-TIPI score improve diagnostic accuracy and triage in patients with chest pain in rural hospitals?
Absolute Event Rate: 89% vs 86.8%
p-value: p=0.15
Routine addition of the ACI-TIPI score did not improve diagnostic accuracy or significantly change triage for chest pain patients in rural emergency departments.
ACI-TIPI failed to improve rural triage or accuracy; leaves open its role outside urban EDs and requires prospective validation before adoption.
PURPOSE: The Acute Cardiac Ischemia Time-Insensitive Predictive Instrument (ACI-TIPI) has been shown to improve diagnostic accuracy of acute cardiac ischemia (ACI) and decrease coronary care unit admissions in urban emergency departments. The purpose of this study was to determine the impact of the ACI-TIPI on triage and diagnosis of patients with chest pain in rural hospitals. METHODS: We undertook a controlled trial of the impact ACI-TIPI use in the High Plains Research Network (HPRN). Main outcome measures were the triage of patients in emergency departments (admission, transfer, or discharge home) and diagnostic accuracy. RESULTS: There were 1,861 patients seen during a 10-month period. Forty-five percent of all patients complaining of chest pain were discharged home from the emergency department. Eight percent were transferred from the emergency department, and another 10% were transferred later after admission. Among patients with acute myocardial infarction or unstable angina, 22.2% were transferred directly from the emergency department and only 3% were discharged home when ACI-TIPI was available, compared with 18.7% transferred and 5.2% discharged home when not available (P = .4). Diagnostic accuracy was high and not statistically different with the addition of the ACI-TIPI score (86.8% ACI-TIPI off vs 89.0% ACI-TIPI on, P = .15), CONCLUSIONS: Physicians in the HPRN provided appropriate diagnosis and triage to patients with chest pain. Routine addition of the ACI-TIPI score did not improve diagnostic accuracy or significantly change triage. Further research on ACI-TIPI in rural hospitals is necessary before recommending routine use of the ACI-TIPI.
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John M. Westfall (2006) conducted an RCT in Chest pain or symptoms suggestive of acute cardiac ischemia (n=1,861). ACI-TIPI (Acute Cardiac Ischemia Time-Insensitive Predictive Instrument) score vs. Standard ECG report (ACI-TIPI off) was evaluated on Diagnostic accuracy for acute myocardial infarction (p=0.15). Routine addition of the ACI-TIPI score to standard ECG reports did not significantly improve diagnostic accuracy (89.0% vs 86.8%, P=0.15) or change triage decisions for patients with chest pain in rural hospitals.
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