Answers are grounded in this paper and cite their sources.
The properties of neutralization of antigens of canine distemper virus Onderstepoort and a recent field isolate, KDK-1, were investigated with strain-specific dog sera. A conventional neutralization assay indicated antigenic dissimilarity between the strains; however, when guinea pig complement was included in the reaction mixture, the strains were neutralized with not only the homologous but also the heterologous antibodies.
No takes yet. Share an insight, caveat, or question.
Mochizuki et al. (2002) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: