ymphoma (malignant lymphoma, lymphosarcoma, LSA) is defined as a lymphoid malignancy that originates from solid organs (eg, lymph nodes, liver, spleen).This differentiates lymphomas from lymphoid leukaemias, which originate in the bone marrow. Etiology and epidemiologyPrevious reports document that approximately 70% of cats with lymphoma are feline leukaemia virus (FeLV)-positive.The prevalence of viraemia in cats with lymphoma varies with the anatomical form of presentation but, in general, young cats with lymphoma are FeLV-positive, whereas older cats are FeLV-negative.Over the past few years, the prevalence of FeLV infection in cats with lymphoma in our clinic is decreasing.Feline immunodeficiency virus (FIV) infection significantly increases the risk of developing lymphoma.The age of presentation in cats with lymphoma is bimodal; the first peak occurs at approximately 2 years of age and the second one at approximately 10-12 years of age.The first peak is composed mainly of FeLV-positive cats, whereas the second one includes predominantly FeLVnegative cats.The mean age of presentation of lymphoma in FeLV-positive cats is 3 years, whereas in FeLV-negative cats it is 7-8 years. Clinical featuresFour anatomic forms of presentation are recognised in cats and dogs with lymphoma:
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C. Guillermo Couto (2000) studied this question.
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