Pyoderma gangrenosum controlled with rituximab

Pyoderma gangrenosum (PG) is a rare inflammatory cutaneous disease. Much of the underlying pathophysiology and etiology remain poorly understood, but PG is often associated with autoimmunity and chronic inflammatory and/or neoplastic diseases.1,2 The disease can be extremely variable in presentation with either single or multiple lesions presenting on various parts of the body.