Doppler Evaluation of Fetoplacental and Uteroplacental Circulation Outcomes in Women With Pre-Eclampsia: Comparison and Correlation Between Different Doppler Parameters

Background: Preeclampsia (PE) affects between 5% and 8% of all pregnancies and is one of the leading cause of maternal mortality in underdeveloped countries.PE is characterized by the new onset of high blood pressure and proteinuria with or without body swelling that occurs after 20 weeks of gestation and lasts up to 6 weeks after labor.The pathophysiology of PE is based on the incapability of the trophoblast to invade the myometrium properly causing improper remodeling of spiral arteries resulting in fetoplacental insufficiency and this can be detected by using Doppler ultrasound.Objective: To compare and correlate among cerebroplacental ratio (CPR), uterine artery, umbilical artery, and middle cerebral artery (MCA) parameters outcomes in established cases of pre-eclampsia Patients and methods: A total 36 cases of pregnant women who were diagnosed clinically and by laboratory investigation as preeclampsia were included in this study in cross-sectional study to evaluate fetoplacental and uteroplacental circulation using Doppler parameters such as pulsatility index (PI) and cerebroplacental ratio.Results: There was a strong correlation between the cerebroplacental ratio and Middle cerebral artery PI (p-value =0.0006); however, a minimum positive correlation was found between CPR and umbilical artery (UmA) and uterine artery (UTA) p=0.0274 and 0.0244 respectively Conclusion: A positive correlation found between CPR PI and MCA, UTA, UmA pulsatility indices; therefore, we conclude that they can be used as complementary to each other in we conclude that they can be used as complementary to each other for identifying high-risk pregnancies, early detection of fetal compromise and consequently optimizing the timing of intervention.