World Gastroenterology Organisation Global Guideline: Helicobacter pylori in Developing Countries

In developing countries, H. pylori infection is a public health issue. The high prevalence of the infection means that public health interventions may be required. Therapeutic vaccination is probably the only strategy that would make a decisive difference in the prevalence and incidence of H. pylori throughout the world. The short-term approach, however—provided that resources allow for this—would be a test-and-treat strategy for those who are at risk for PUD or gastric cancer and for those with troublesome dyspepsia.