Two artifactual secoiridoid glucosides, 7-O-butylsecologanic acid [5] and secologanin dibutylacetal [6], have been isolated from a butanol extract of Lonicera japonica, along with loganin, sweroside, and secologanin [4]. Evidence is provided chat shows acetalic iridoids can be easily formed by reaction of the aldehydic function with alcoholic solvents.
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Tomassini et al. (1995) studied this question.