Key result
Near-infrared spectroscopy based tissue haemoglobin index showed a bias of -0.02 g/L and precision of 5.41 g/L, and is currently not suitable for monitoring haemoglobin concentration in children.
Why the study?
Does near-infrared spectroscopy based tissue haemoglobin index accurately monitor haemoglobin concentration compared to blood samples in paediatric surgical patients?
Observational (n=40)
Does near-infrared spectroscopy based tissue haemoglobin index accurately monitor haemoglobin concentration compared to blood samples in paediatric surgical patients?
Effect estimate: bias -0.02 g.l(-1), precision 5.41 g.l(-1)
The tissue haemoglobin index derived from near-infrared spectroscopy is currently not suitable for monitoring haemoglobin concentration in children undergoing surgery.
Should not replace blood sampling for haemoglobin monitoring in children; further validation studies needed before clinical adoption.
We evaluated the near-infrared spectroscopy based tissue haemoglobin index for continuous non-invasive monitoring of haemoglobin concentration during paediatric surgery. Blood samples from 40 children (from birth to 16 years old) were analysed oximetrically. From the first blood sample the tissue haemoglobin index/haemoglobin concentration coefficient was calculated for further tissue haemoglobin index-derived haemoglobin concentrations in each patient. Comparison of corresponding values revealed a bias and precision of -0.02 and 5.41 g.l(-1), respectively. Sensitivity and specificity of tissue haemoglobin index were 73.1% and 70.0%, respectively, for predicting falling haemoglobin concentration values. Currently, the tissue haemoglobin index is not suitable for monitoring haemoglobin concentration in children undergoing surgery.
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Dullenkopf et al. (2004) conducted an observational in paediatric surgery (n=40). near-infrared spectroscopy based tissue haemoglobin index vs. oximetrically analysed blood samples was evaluated on bias and precision of tissue haemoglobin index-derived haemoglobin concentrations (bias -0.02 g.l(-1), precision 5.41 g.l(-1)). Near-infrared spectroscopy based tissue haemoglobin index showed a bias of -0.02 g/L and precision of 5.41 g/L, and is currently not suitable for monitoring haemoglobin concentration in children.
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