Key result
Endothelial function assessment guides risk stratification and management in CAD.
Why the study?
The clinical management of CAD has traditionally focused on anatomical features, but the dynamic role of endothelial function in vascular physiology has gained importance.
Non-invasive assessment of endothelial function Risk assessment and clinical management of patients with coronary artery disease (CAD) has traditionally concen- trated on the anatomical features of atherosclerosis.Over the past decade,-however, the importance of the dynamic aspects of vascular physiology, particularly the role of the endothelium, have become clear.In 1980, Furchgott demonstrated the production of a relaxant factor from healthy endothelium (EDRF),' which has subsequently
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Mullen et al. (1997) conducted a review in Coronary artery disease (CAD). Non-invasive assessment of endothelial function was evaluated. The importance of the dynamic aspects of vascular physiology, particularly the role of the endothelium, has become clear in the risk assessment and management of coronary artery disease.
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