Key result
Asian patients receiving neuroleptics experienced significantly more frequent acute extrapyramidal side effects compared to black and white patients.
Why the study?
Are Asian patients more vulnerable to acute extrapyramidal side effects of neuroleptics compared to black and white patients?
Population
80 patients (20 Asian, 20 black, and 40 white) treated with neuroleptics
Comparison
Asian ethnicity (observational exposure) vs Black and white ethnicity
Design
Cohort
Authors
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May prompt closer EPS monitoring in Asian patients on neuroleptics; hypothesis-generating and requires replication before practice change.
Are Asian patients more vulnerable to acute extrapyramidal side effects of neuroleptics compared to black and white patients?
Asian patients appear to be significantly more vulnerable to acute extrapyramidal side effects from neuroleptics compared to black and white patients.
Binder et al. (1981) studied this question. Asian patients receiving neuroleptics experienced significantly more frequent acute extrapyramidal side effects compared to black and white patients.
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