Key result
Greater left atrial sphericity linked to ~26% higher risk of thromboembolism in AF.
Why the study?
Left atrial sphericity is a novel remodeling parameter with potential to improve thromboembolic risk prediction in atrial fibrillation patients beyond standard clinical scores.
Does left atrial sphericity improve risk prediction of thromboembolic events compared to standard clinical risk scores in patients with atrial fibrillation?
Comparison
Left atrial sphericity vs CHAD and CHA2DS2-VASc scores, LA volume, LAA volume
Design
Case-control study using 3D left atrial reconstruction
Authors
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Left atrial sphericity may identify higher thromboembolic risk in AF; hypothesis-generating and should not yet alter practice or scores.
Case-Control (n=58)
Does left atrial sphericity improve risk prediction of thromboembolic events compared to standard clinical risk scores in patients with atrial fibrillation?
Odds Ratio: 1.26 (95% CI 1.85–52.2)
p-value: p=0.013
Left atrial sphericity assessed by 3D reconstruction improves the prediction of thromboembolic events in atrial fibrillation beyond standard clinical risk scores.
Bisbal et al. (2016) conducted a case-control in Atrial Fibrillation (n=58). Left atrial sphericity (LASP) vs. Patients without prior thromboembolic events was evaluated on Prior thromboembolic events (OR 1.26, 95% CI 1.85-52.20, p=0.013). Left atrial sphericity was significantly higher in AF patients with prior thromboembolic events (82.5% vs 80.2%) and predicted prior events (OR 1.26; 95% CI 1.85-52.20; P=0.013).
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