Key result
Shorter courses of postsurgical antibiotic therapy for abdominal sepsis are desirable to minimize drug-related adverse events, antibiotic resistance, and costs.
Discusses the appropriate duration of postsurgical antibiotic therapy for abdominal sepsis, highlighting a study by Sawyer and colleagues.
Major milestones in surgery have included safe sutures to promote tissue integrity, cautery to minimize bleeding, the use of anesthesia to avoid pain, and antisepsis to prevent operative contamination. In the antibiotic era, surgical procedures for source control in abdominal sepsis have been complemented with drugs targeting persistent organisms after luminal inflammation, obstruction, or perforation.The appropriate duration of postsurgical antibiotic therapy has been unclear.1 However, if safe, shorter courses would be desirable to minimize drug-related adverse events, the selection of antibiotic resistance, and costs.In this issue of the Journal, Sawyer and colleagues2 present data from the Study . . .
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Wenzel et al. (2015) conducted an editorial in Abdominal sepsis. Postsurgical antibiotic therapy was evaluated. Shorter courses of postsurgical antibiotic therapy for abdominal sepsis are desirable to minimize drug-related adverse events, antibiotic resistance, and costs.
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