Key result
Systemic hypertension in cats is linked to increased LV wall thickness and altered aortic root dimensions.
Why the study?
The effects of systemic hypertension on echocardiographic and radiographic cardiovascular variables in cats compared with healthy geriatric cats were not well characterized.
Does systemic hypertension cause echocardiographic and radiographic cardiovascular changes in cats?
Case-Control (n=30)
Does systemic hypertension cause echocardiographic and radiographic cardiovascular changes in cats?
p-value: p=0.0001
Systemic hypertension in cats is associated with echocardiographic changes including increased left ventricular wall thickness, asymmetrical septal hypertrophy, and aortic root dilatation.
The purpose of this study was to assess the effects of systemic hypertension (SHT) on echocardiographic and radiographic cardiovascular variables in affected cats compared with healthy geriatric cats. Secondary objectives were to determine whether there were any relationships between these findings and age or systolic blood pressure (SBP). Fifteen healthy cats (<8 years of age with normal SBP) and 15 hypertensive cats (SBP > 180 mm Hg) were studied. Each cat was evaluated for standard echocardiographic parameters and 4 different aortic root dimensions. Seventeen variables were measured from right lateral and dorsoventral radio-graphic views. Left ventrical wall thickness was greater in the SHT group (5.1 ± 0.9 mm) than in the healthy cats (4.2 ± 0.5 mm). Left ventricular hypertrophy in the SHT cats often was not severe, and mean measures were considered normal. Some cats had asymmetrical septal hypertrophy (ASH) in the basilar portion of the septum as determined from the 2-dimensional view of the left ventricular outflow tract. ASH was greater in cats with SHT. Comparisons of the proximal ascending aorta indicated the presence of dilatation in the SHT cats, and comparison of the ascending aorta to the aortic annulus was helpful in differentiating between the 2 groups. The distal aortic root measurements and ratios evaluated by echocardiography were significantly different between the 2 groups of cats (P= .0001) and were significantly correlated with SBP (P= .0001) but not age (P > .3).
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Nelson et al. (2002) conducted a case-control in Systemic hypertension (n=30). Systemic hypertension vs. Healthy cats with normal systolic blood pressure was evaluated on Distal aortic root measurements and ratios (p=0.0001). Systemic hypertension in cats was associated with greater left ventricular wall thickness (5.1 vs 4.2 mm) and significant differences in distal aortic root measurements (P=0.0001).
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