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The recent review on autophagy by Pallet et al published in the Journal addresses the interesting possibility to promote autophagy to limit ischemia-reperfusion injury (IRI) and reduce delayed graft function after kidney transplantation (1). Indeed, autophagy is generally regarded as a protective response to various types of pathological injuries—among them renal IRI—and its stimulation may therefore improve graft outcome.
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Decuypere et al. (2014) studied this question.
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