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Purpose: Mayaro virus (MAYV) is an emerging alphavirus circulating in Central/South America. It is transmitted to humans by mosquito bites, causing a febrile illness often with prolonged joint inflammation which resembles other infections with co-circulating arboviruses e.g. Dengue (DENV), Chikungunya (CHIKV) or Oropouche virus (OROV). Serological differentiation from alphavirus infections is complicated by antibodies targeting homologous antigens from related viruses (Semliki Forest virus complex), primarily CHIKV.
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Soane et al. (2019) studied this question.
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