Key result
Paroxysmal AF is linked to prolonged atrial electromechanical delay that correlates with CHA2DS2-VASc scores.
Why the study?
The relationship between atrial electromechanical delay times and CHA2DS2-VASc scores in patients with paroxysmal atrial fibrillation was not well defined.
Is there a correlation between atrial electromechanical delay times and CHA2DS2-VASc scores in patients with paroxysmal atrial fibrillation?
Case-Control (n=74)
Is there a correlation between atrial electromechanical delay times and CHA2DS2-VASc scores in patients with paroxysmal atrial fibrillation?
p-value: p=<0.001
Atrial electromechanical delay times are prolonged in patients with paroxysmal atrial fibrillation and correlate with the CHA2DS2-VASc score, suggesting a potential link to thromboembolic risk.
AIM: This study aims to evaluate the relationship between atrial electromechanical delay (AEMD) times and CHA2DS2-VASc scores in patients diagnosed with paroxysmal atrial fibrillation (PAF). MATERIALS AND METHODS: The study included a total of 74 patients, 34 of whom were diagnosed with PAF and 40 were included in the control group. The CHA2DS2-VASc score was calculated for each patient. Additionally, blood samples were taken from all patients and transthoracic echocardiographic measurements were made. Left atrial mechanical functions and AEMD were calculated. RESULTS: Mean CHA2DS2-VASc score measured was 2.24 ± 1.53 in PAF group. There was no significant difference between the groups when the patients were evaluated for baseline characteristics and laboratory parameters (P > 0.05) The echocardiographic evaluation of LA mechanical functions showed that only LA minimum volume (19 ± 6.4 vs. 16.7 ± 4.6, P = 0.02) and LA presystolic volume (28.9 ± 7 vs. 25.1 ± 5.7, P = 0.01) were higher in the PAF group. When AEMD was compared between the groups; lateral PA, septal PA, tricuspid PA, Interatrial EMD, and intraatrial EMD were significantly extended compared to control group (P < 0.001) CHA2DS2-VASc score was correlated with Lateral atrial PA (P < 0.001, r = 0.524), Septal atrial PA (P < 0.001, r = 0.45), Interatrial EMD (P < 0.001, r = 0.54), and intraatrial EMD (P < 0.001, r = 0.51) times. CONCLUSION: The present study shows that AEMD times increase in patients with PAF compared to the control group. Furthermore, this study revealed a correlation between AEMD times and CHA2DS2-VASc score, as well showed that extended AEMD time may be associated with thromboembolism risk.
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Nar et al. (2014) conducted a case-control in Paroxysmal atrial fibrillation (n=74). Paroxysmal atrial fibrillation vs. Control group was evaluated on Atrial electromechanical delay (AEMD) times and correlation with CHA2DS2-VASc score (p=<0.001). Paroxysmal atrial fibrillation was associated with significantly extended atrial electromechanical delay times compared to controls (P<0.001), which correlated with CHA2DS2-VASc scores (r=0.45-0.54).
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