Key result
Prostate cancer survivorship 10 years post-diagnosis was associated with higher prevalence of clinically significant and severe depression compared to age-matched non-PCa men.
Why the study?
What is the prevalence and nature of depression in prostate cancer survivors 10 years after treatment?
Cross-Sectional (n=146)
What is the prevalence and nature of depression in prostate cancer survivors 10 years after treatment?
Prostate cancer survivors experience higher rates of clinically significant depression, particularly anhedonia, 10 years post-treatment compared to the general population, highlighting the need for targeted psychological support.
Elevated depression rates in long-term PCa survivors warrant screening consideration; hypothesis-generating for survivorship care integration.
To describe the prevalence, severity and nature of depression in a sample of prostate cancer (PCa) survivors 10 years after diagnosis and treatment, 146 Australian patients from the RADAR trial who received their diagnosis 10 years previously completed the Zung Self-rating Depression Scale and a background questionnaire. Prevalence rates for clinically significant depression and severe depression were higher than those reported for the non-PCa men of the same age in Australia. The most common subtype of depression was Anhedonia, followed by Cognitive depression. Change in eating habits was the most powerful depression symptom predicting Anhedonia. By providing the first detailed documentation of major depression prevalence in PCa survivors, plus describing the nature of that depression, these data suggest that there is an ongoing need to provide treatments for these men and that those treatments should be focussed upon loss of previously available sources of enjoyment.
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Sharpley et al. (2016) conducted a cross-sectional in Prostate cancer (n=146). Prostate cancer survivorship vs. Non-PCa men of the same age was evaluated on Prevalence of clinically significant and severe depression. Prostate cancer survivorship 10 years post-diagnosis was associated with higher prevalence of clinically significant and severe depression compared to age-matched non-PCa men.
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