Answers are grounded in this paper and cite their sources.
IL-1 cytokines constitute a family of biologically active proteins with pleiotropic function especially in immunity. Both protective as well as deleterious properties of individual IL-1 family cytokines in tumor biology have been described. The function of IL-1-family cytokines depends on the producing source, the present (inflammatory) microenvironment and N-terminal proteolytical processing. Each of these determinants is shaped by different modes of cell death. Here we summarize the properties of IL-1 family cytokines in tumor biology, and how they are modulated by cell death.
No takes yet. Share an insight, caveat, or question.
Mora et al. (2016) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: