Key result
The rotavirus positivity rate in Iranian children <5 years of age hospitalized for acute gastroenteritis ranged from 15.3% to 67.6%, with G1P[8] as the most common genotype.
Rotavirus is a significant cause of acute gastroenteritis in Iranian children under 5, with G1P[8] being the predominant genotype.
Supports rotavirus surveillance and vaccine planning in Iran; leaves open questions on post-vaccination genotype shifts.
Rotaviruses are a major cause of severe diarrhea in children <5 years of age worldwide. The rotavirus positivity rate in Iran was 15.3% to 67.6% in all patients <5 years of age hospitalized for acute gastroenteritis, which was significantly higher than recorded in outpatient departments. Moreover, the most commonly detected genotype was G1P[8], although in a single study a peak prevalence of the G4P[8] genotype was reported.
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Shoja et al. (2012) conducted a review in acute gastroenteritis. Rotavirus infection was evaluated on Rotavirus positivity rate. The rotavirus positivity rate in Iranian children <5 years of age hospitalized for acute gastroenteritis ranged from 15.3% to 67.6%, with G1P[8] as the most common genotype.
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