Key result
Pleural fluid LDH levels in modified transudates accurately differentiated cardiac from non-cardiac diseases (AUC 0.878, cut-off <535 U/L) and feline infectious peritonitis from other diseases (AUC 0.849, cut-off >641 U/L).
Why the study?
Does pleural fluid LDH measurement help differentiate the etiology of modified transudate pleural effusion in cats?
Cross-Sectional (n=122)
No
Does pleural fluid LDH measurement help differentiate the etiology of modified transudate pleural effusion in cats?
Effect estimate: AUC 0.878 (95% CI 0.781-0.974)
p-value: p=<0.001
Pleural fluid LDH can be a useful adjunctive marker for differentiating cardiac from non-cardiac causes and FIP from non-FIP causes of modified transudate pleural effusion in cats.
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May aid differentiation of cardiac vs. non-cardiac causes in feline modified transudates; leaves open prospective validation before routine use.
Hla et al. (2022) conducted a cross-sectional in Pleural effusion (n=122). Pleural fluid LDH measurement vs. Non-cardiac diseases was evaluated on Area under the curve (AUC) of pleural fluid LDH for predicting cardiac disease etiology in modified transudate (AUC 0.878, 95% CI 0.781-0.974, p=<0.001). Pleural fluid LDH levels in modified transudates accurately differentiated cardiac from non-cardiac diseases (AUC 0.878, cut-off <535 U/L) and feline infectious peritonitis from other diseases (AUC 0.849, cut-off >641 U/L).
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