Purpose This paper aims to examine how reductionist explanations of mental illness shape stigma and help-seeking in India. It argues for moving beyond predominantly biogenetic or psychological explanations toward culturally responsive mental health communication that integrates biological, psychological and sociological perspectives. Design/methodology/approach This conceptual and reflective paper draws on clinical practice, mental health education and community engagement in Northeast India to examine how medical, biogenetic, psychological and sociological explanations shape understandings of mental illness. It critically reflects on the limitations of reductionist approaches and advocates culturally responsive mental health communication. Findings The paper highlights that medical or biogenetic explanations may reduce moral judgments but can reproduce stigma through diagnostic labeling. They may facilitate help-seeking while creating barriers to psychological engagement. Conversely, excessive psychologization may underemphasize biological factors. The paper therefore emphasizes integrating biological, psychological and sociological perspectives within culturally responsive mental health communication. Practical implications Mental health communication and public health programmes should avoid relying exclusively on biogenetic or psychological explanations. Clinicians and educators should integrate biological, psychological and sociocultural perspectives while using language that resonates with local idioms of distress and lived experiences. Such an approach may improve understanding of mental illness, strengthen engagement with psychological and pharmacological interventions and reduce the cultural distance between professional explanations and community beliefs. The paper also highlights the need to communicate psychiatric diagnoses in ways that are meaningful and accessible to patients and families, rather than treating diagnostic labels as sufficient explanations of suffering. Originality/value The paper offers a distinctive critique of stigma-reduction approaches by examining how changing explanatory frameworks may transform, rather than eliminate, stigma. Its originality lies in bringing together the medical, psychological, sociological and cultural dimensions of mental illness communication, drawing particularly on clinical and community experiences from Northeast India. It highlights the tension between biogenetic reductionism and excessive psychologization, while proposing a more pluralistic and culturally responsive approach. The paper adds value by emphasizing local idioms of distress and the need to bridge professional psychiatric explanations with patients’ lived meanings, with implications for mental health education, public health communication and clinical engagement.
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Chandrasen Yadav (2026) studied this question.
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