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It is important to stage fibrosis in chronic hepatitis for 2 purposes: to select candidates for therapy and to follow fibrosis progression/regression on treatment. Chronic viral hepatitis is a prolonged inflammatory disease of the liver that may lead to the progressive development of fibrosis. Because fibrosis and its end-point cirrhosis are the main causes of morbidity and mortality, fibrosis assessment is considered as the most relevant information for the evaluation of the severity of the disease and as a useful indicator for prognosis and treatment decision.
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Asselah et al. (2014) studied this question.
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