Why the study?
Management of chronic antithrombotic therapy in women undergoing gynecologic surgery requires balancing hemorrhagic and thromboembolic risks, with individualized perioperative planning.
This committee opinion highlights the need for individualized, multidisciplinary perioperative management of antithrombotic therapy in gynecologic surgery to balance bleeding and thrombotic risks.
Answers are grounded in this paper and cite their sources.
Early preoperative assessment may guide antithrombotic management in gynecology; leaves open need for prospective validation of timing strategies.
Surgery can present a management dilemma for gynecologists whose patients receive chronic antithrombotic therapy because the risk of hemorrhagic complications must be balanced against the risk of thromboembolic complications. Interruption of antithrombotic therapy to reduce perioperative bleeding poses a significant risk of recurrent thromboembolic events. Patients who receive chronic antithrombotic therapy should be seen at least 7 days before a planned procedure, and each woman should be included in decision making regarding risks and benefits specific to her situation. The schedule may need to be altered if the international normalized ratio is at a high level and in patients older than 75 years of age (who may need more time to correct their international normalized ratio). The patient's cardiologist often will have recommendations for the appropriate bridging therapy for a specific valve or stent. A discussion of the risks and benefits of different management schemes for chronic antithrombotic therapy may involve the surgeon, the patient, the anesthesiologist, and the primary care physician.
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A 2014 study conducted a review in Gynecologic surgery in patients on chronic antithrombotic therapy. Perioperative management of chronic antithrombotic therapy was evaluated. Perioperative management of chronic antithrombotic therapy in gynecologic surgery requires individualized, multidisciplinary planning to balance hemorrhagic and thromboembolic risks.
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