Key result
Facilitated PCI transfer strategies compare unfavorably to very early thrombolysis in acute MI.
Why the study?
Randomised trials have established PCI as the best reperfusion strategy for most AMI patients, but their applicability to routine practice is limited and modern trials must consider logistics, transfer times, and adjunctive drug treatment during transfer compared to very early thrombolysis.
Does transfer for primary PCI or facilitated PCI improve outcomes compared to very early thrombolysis in patients with acute myocardial infarction?
Does transfer for primary PCI or facilitated PCI improve outcomes compared to very early thrombolysis in patients with acute myocardial infarction?
Answers are grounded in this paper and cite their sources.
This paper highlights the need for modern trials to evaluate the real-world logistics, transfer times, and adjunctive therapies of primary PCI compared to early thrombolysis in acute myocardial infarction.
Randomised trials have led to the conclusion that percutaneous coronary intervention (PCI) is the best reperfusion strategy for most patients with acute myocardial infarction (AMI). However, these trials have limited application to routine practice. Modern trials of mechanical reperfusion strategies need to take account of logistics, transfer times, and adjunctive drug treatment during transfer (facilitated PCI). Such PCI protocols need to be judged against very early thrombolysis with modern agents. This has been the thrust behind a series of recent studies addressing these "real world" issues in early AMI management
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Miles C. D. Dalby (2002) conducted a review in Acute myocardial infarction (AMI). Percutaneous coronary intervention (PCI) vs. Early thrombolysis was evaluated. Recent studies address real-world issues in early AMI management, comparing facilitated PCI protocols involving transfer logistics against very early thrombolysis.
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