Key result
Prophylactic temporary RV pacing linked to ~4-fold higher VF during coronary arteriography.
Why the study?
The need for temporary transvenous pacing during coronary arteriography in patients with chronic bundle branch block was uncertain.
Does prophylactic temporary transvenous pacing increase the risk of ventricular arrhythmias in patients with chronic bundle branch block undergoing coronary arteriography?
Cohort (n=217)
Does prophylactic temporary transvenous pacing increase the risk of ventricular arrhythmias in patients with chronic bundle branch block undergoing coronary arteriography?
Absolute Event Rate: 9% vs 2%
p-value: p=<0.05
Routine prophylactic pacemaker insertion during coronary arteriography in patients with chronic bundle branch block is unnecessary and may increase the risk of iatrogenic ventricular fibrillation.
A retrospective analysis of 217 consecutive patients with chronic bundle branch blocks undergoing cardiac catheterization was done to evaluate the need for temporary transvenous pacing during coronary arteriography. In patients without temporary right ventricular pacemakers (n = 185), only one episode of high-grade atrioventricular block occurred during coronary arteriography which required the urgent use of temporary pacing. All other bradyarrhythmias, including five episodes of transient asystole (greater than 3-sec pause) and four episodes of atrioventricular block (second degree or higher) were successfully managed without pacemaker utilization. Patients with prophylactic right ventricular pacemakers (n = 32) had a greater prevalence of ventricular fibrillation than those without pacing electrodes located in the right ventricle (2% vs. 9% respectively; P less than 0.05). These findings suggest that routing prophylactic pacemaker insertion during coronary arteriography in patients with chronic bundle branch block is not warranted and may place the patient at risk for developing iatrogenic ventricular arrhythmias.
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Gilchrist et al. (1988) conducted a cohort in Chronic bundle branch block (n=217). Prophylactic temporary right ventricular pacemakers vs. No temporary right ventricular pacemakers was evaluated on Ventricular fibrillation (p=<0.05). Prophylactic temporary right ventricular pacemakers during coronary arteriography in patients with chronic bundle branch block were associated with a higher prevalence of ventricular fibrillation compared to no pacemaker (9% vs 2%; P<0.05).
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