Key result
Glutaraldehyde scrubbing facilitates mitral valve repair in active infective endocarditis by reinforcing fragile tissue.
Why the study?
Mitral valve repair in active infective endocarditis is challenging due to fragile infected tissue requiring decontamination and reinforcement.
Case Report (n=1)
No
Glutaraldehyde application during mitral valve repair for active infective endocarditis may help decontaminate and reinforce fragile infected tissue.
May aid infected mitral repair; single case leaves open need for prospective validation before practice consideration.
We report the use of glutaraldehyde (GA) in a case of valve repair for mitral valve prolapse associated with active infective endocarditis. GA scrubbed at the site of infection decontaminates and reinforces infected fragile tissue, avoids excessive debridement, and strengthens the edges of valve leaflets to facilitate suturing.
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Isoda et al. (2018) conducted a case report in Active infective endocarditis (n=1). Glutaraldehyde (0.6% solution) was evaluated on Successful mitral valve repair and postoperative recovery. Intraoperative scrubbing of infected mitral valve leaflets with 0.6% glutaraldehyde solution facilitated successful valve repair by decontaminating and reinforcing fragile tissue in a patient with active infective endocarditis.
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