THE serious loss of vision which commonly follows a rise in intra-ocular pressure is a familiar clinical experience, but the characteristics of the rate or type of visual loss are not necessarily proportional to the degree of rise in pressure, nor to the length of time for which it operates.Since it is impossible to predict precisely the amount or rate of visual loss from the degree of elevation of the intra-ocular pressure, it is reasonable to postulate that some other factor or factors determine the vulnerability of the nervous elements of the eye to a pathological rise in pressure.In general, body tissues, especially nervous cells, depend on an adequate blood supply for normal-functioning, and it may be that modification of the circulation of blood within the eye by a rise in intra-ocular pressure plays a part in determining the loss of visual function in glaucoma.With these ideas in mind we have attempted to devise a method for studying certain aspects of the vascular circulation inside the eye.Schubert (1936), using diascleral illumination in albino rabbits, was able
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Broadfoot et al. (1961) studied this question.