Key result
Inelastic compression plus anticoagulation reduces acute thrombus extension in deep venous thrombosis.
Why the study?
Use of compression therapy to reduce postthrombotic syndrome incidence in deep venous thrombosis patients is controversial with no consensus on compression type or duration.
Inelastic compression therapy combined with anticoagulation in the acute phase of deep venous thrombosis may reduce thrombus extension, though prospective studies are needed to evaluate its effectiveness.
Answers are grounded in this paper and cite their sources.
Anticoagulation plus inelastic compression may limit acute DVT extension; prospective trials needed to confirm PTS benefit.
Use of compression therapy to reduce the incidence of postthrombotic syndrome among patients with deep venous thrombosis is a controversial subject and there is no consensus on use of elastic versus inelastic compression, or on the levels and duration of compression. Inelastic devices with a higher static stiffness index, combine relatively small and comfortable pressure at rest with pressure while standing strong enough to restore the "valve mechanism" generated by plantar flexion and dorsiflexion of the foot. Since the static stiffness index is dependent on the rigidity of the compression system and the muscle strength within the bandaged area, improvement of muscle mass with muscle-strengthening programs and endurance training should be encouraged. Therefore, in the acute phase of deep venous thrombosis events, anticoagulation combined with inelastic compression therapy can reduce the extension of the thrombus. Notwithstanding, prospective studies evaluating the effectiveness of inelastic therapy in deep venous thrombosis and post-thrombotic syndrome are needed.
No takes yet. Share an insight, caveat, or question.
Eduardo Simões Da Matta (2017) conducted a review in Deep venous thrombosis and post-thrombotic syndrome. Compression therapy vs. Non-compression was evaluated. Anticoagulation combined with inelastic compression therapy can reduce the extension of the thrombus in the acute phase of deep venous thrombosis.
Synapse has enriched 10 related papers. Consider them for comparative context: