Key result
Cibenzoline triggers severe fasting hypoglycemia with neurologic depression and hyperkalemia in an elderly patient.
Why the study?
Antiarrhythmic-induced hypoglycemia is an ill-defined phenomenon with limited reported cases, particularly involving cibenzoline.
Comparison
Exposure to cibenzoline vs no exposure
Design
Case report
Authors
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Cibenzoline may induce hypoglycemia in elderly HF patients; this case leaves open incidence and mechanisms for prospective study.
Case Report (n=1)
Cibenzoline, a class I antiarrhythmic agent, can cause severe fasting hypoglycemia, highlighting the need for clinical awareness of this rare adverse effect.
Hilleman et al. (1987) conducted a case report in Ventricular arrhythmias (n=1). Cibenzoline was evaluated on Hypoglycemia. Cibenzoline therapy induced severe fasting hypoglycemia (blood glucose 21-40 mg/dL) with central nervous system depression and hyperkalemia in an elderly male after two years of treatment.
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