Key result
Renal failure, vasopressors, and anterior MI are associated with higher in-hospital mortality in AMI-cardiogenic shock.
Why the study?
Cardiogenic shock remains the leading cause of in-hospital mortality in patients presenting with acute myocardial infarction, necessitating investigation of clinical characteristics and mortality predictors.
Observational
No
In-hospital mortality for AMI complicated by cardiogenic shock remains high at 60%, with renal failure, late shock onset, hyperglycemia, and anterior MI being major predictors.
May aid risk stratification in AMI cardiogenic shock; hypothesis-generating for targeted interventions.
Background Cardiogenic shock CS is still the leading cause of in hospital mortality in patients presenting with acute myocardial infarction AMI Aim To investigate the epidemiological and clinical characteristics of a series of patients hospitalized for AMI complicated by CS and to determine the in hospital mortality Methods We retrospectively analysed patients affected by AMI complicated by CS admitted to cardiology department of the military hospital between October and April Results A total of patients were included in the study patients were male The mean age was plusmn years Diabetes mellitus and hypertension were the predominant risk factors On admission of patients were in left ventricular failure and in shock The mean LVEF was plusmn Thrombolysis was performed in of patients Seventy two of patients underwent angiography and had percutaneous coronary intervention PCI Of these were taken for primary PCI and had rescue PCI Revascularization was complete in of cases The success rate of PCI was The average of hospital stay was plusmn days Patients revealed a mortality rate of occurring on average in the th day of hospitalization We found that renal failure p late onset of shock p hyperglycemia p leukocytosis p use of vasopressors p and the anterior territory of MI p were significantly predictive of hospital mortality Conclusion Despite significant advances in the treatment of myocardial infarction the in hospital mortality of patients in CS complicating MI remains high Renal failure late onset of shock hyperglycemia and the anterior territory of MI were the major predictive of hospital mortality A multidisciplinary approach including medical actors and pre hospital centers specialized in the treatment of this condition is actually necessary
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A 2016 study conducted an observational in Acute myocardial infarction complicated by cardiogenic shock. Clinical and epidemiological risk factors was evaluated on In-hospital mortality. In patients with acute myocardial infarction complicated by cardiogenic shock, renal failure, late onset of shock, hyperglycemia, leukocytosis, use of vasopressors, and anterior MI predicted mortality.
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