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The influence of genetic factors has been suggested from the earliest descriptions of obsessive-compulsive disorder (OCD), and a number of studies have been conducted to determine to what extent OCD is heritable. Evidence for the influence of genetic factors has come from twin and family aggregation studies. Furthermore, drug-treatment and functional neuroimaging studies have added strength to the genetic investigations by emphasizing the neurobiologic aspects of OCD.
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Pauls et al. (1999) studied this question.
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