Comparison of Quantitative EEG Indices of the Patients with Alzheimer and Parkinson

Background and Aims:The two common age-related neurological Alzheimer`s Disease (AD) and Parkinson's disease Dementia (PDD) both involve the people with behavioral and cognitive problems.The brain waves of these people change and affect their brain functions.Methods: Forty patients suffering from Alzheimer Disease and 12 patients with Parkinson Dementia and 40 healthy subjects were included in the study.The mean absolute power and mean coherence of brain waves were studied using brain waves analysis with QEEG method.Results: The results showed that mean absolute power of Delta and Theta waves in PDD subjects was higher than those of the AD and control groups, but the absolute power mean of Alpha in Parkinson Dementia patients was lower than that of the Alzheimer and control group; however, the difference between the two dementia groups in terms of Beta absolute power was not significant (P>0.05).There is significant difference between Alpha and Beta bands of the two hemispheres in frontal areas' coherence (F3-F4) (P<0.05),but there is no significant difference in the other areas.Conclusion: QEEG technique can be used as an accurate tool in timely diagnosis of AD and PDD diseases through evaluating the quantitative indices of brain waves.