Key result
Colchicine, ibuprofen, and methimazole completely resolve Graves-associated acute pericarditis in a case report.
Why the study?
Acute pericarditis is an uncommon but significant complication of Graves' disease that requires clinical awareness for diagnosis and treatment.
Case Report (n=1)
No
This case report emphasizes the need to evaluate for thyroid dysfunction, specifically Graves' disease, in patients presenting with idiopathic acute pericarditis.
May support colchicine plus antithyroid therapy in Graves'-associated pericarditis; hypothesis-generating and requires prospective confirmation.
Acute pericarditis is an uncommon but significant complication of Graves' disease. This case report describes a 53-year-old female presenting with acute pericarditis in the context of newly diagnosed Graves' disease. The patient's clinical presentation, diagnostic evaluation, treatment course, and outcome are discussed. We also provide a comprehensive review of the literature on pericarditis associated with Graves' disease, including its pathophysiology, clinical features, diagnostic challenges, and therapeutic approaches. This report highlights the importance of considering thyroid dysfunction in cases of idiopathic pericarditis, as prompt diagnosis and targeted treatment can significantly improve outcomes.
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Santos et al. (2025) conducted a case report in Acute pericarditis associated with Graves' disease (n=1). Colchicine, ibuprofen, and methimazole was evaluated on Resolution of symptoms and pericardial effusion. Treatment with colchicine, ibuprofen, and methimazole resulted in complete resolution of symptoms and pericardial effusion in a 53-year-old woman with Graves' disease-associated acute pericarditis.
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